Navigator News (Coverage Ranks) Business40966 Production1776 Products1695 Brands1690 Drugs818 Celebrex 46 Celebrex Pharmaceuticals Pfizer Inc 39 Diseases Pains Related Events U.S. Painkiller Crisis 15 American Markets 2 U.S. Markets 2

$894 million deal ends pain of Pfizer's lawsuits TRENTON, N.J. - Drug giant Pfizer Inc. has reached an $894 million deal to settle the bulk of the lawsuits over its withdrawn pain reliever Bextra, following the lead of rival Merck & Co., which is spending five times as much to settle Vioxx suits.   Nations:U.S.   Activities:U.S. Painkiller Crisis   Source:(AP)   2008-10-17 Study: Older brains don't benefit from painkillers Results from a large government experiment are dimming hopes that two common painkillers can prevent Alzheimer's disease or slow mental decline in older people.   2008-05-13 Pfizer reaches deal with some Celebrex users: report Pfizer Inc has reached tentative deals with some patients who claim to have suffered heart attacks and strokes from taking the company's Celebrex and Bextra pain medicines, the Wall Street Journal said on Friday, citing plaintiff attorneys.   Activities:U.S. Painkiller Crisis   2008-05-02 Celebrex risky in high-risk patients, study finds Doctors should prescribe the lowest doses of Celebrex possible in patients at high risk of heart problems, researchers who did a combined analysis of six studies of the Pfizer Inc pain drug said on Monday.   2008-03-31 Celebrex disrupts heart rhythm in fruit flies Celebrex, an arthritis drug in the same class as the recalled painkiller Vioxx, caused irregular heartbeats in fruit flies and in heart cells taken from laboratory rats, U.S. researchers said on Friday.   2008-01-25 Headlines $894 million deal ends pain of Pfizer's lawsuits 2008-10-17 Study: Older brains don't benefit from painkillers 2008-05-13 Pfizer reaches deal with some Celebrex users: report 2008-05-02 Celebrex risky in high-risk patients, study finds 2008-03-31 Celebrex disrupts heart rhythm in fruit flies 2008-01-25 Pfizer legal win might block some Celebrex lawsuits 2007-11-20 Pfizer profit falls short, Lipitor disappoints 2007-07-18 COX-2 drugs may raise risk of repeat heart attack 2007-01-29 FDA OKs Celebrex as treatment for kids 2006-12-15 Panel backs Celebrex for juvenile arthritis 2006-11-29 Pfizer's Hank McKinnell replaced as CEO 2006-07-28 Ultrasound good, drugs bad for knee injury 2006-07-13 Prices rise for drugs used by elderly: studies 2006-06-21 Jury: Merck Liable for Man's Heart Attack 2006-04-05 Studies: Celebrex May Stop Colon Cancer 2006-04-03 Study Examines Celebrex and Heart Attacks 2006-03-01 Trial Date for Celebrex Suit Set for June 2006-02-27 Study: Supplements Fail to Ease Arthritis 2006-02-22 Pfizer Profit Forecast Below Projections 2006-02-10 Pfizer 4Q Profit Slips As Revenue Falls 2006-01-19 FDA Approves Celebrex for Spinal Arthritis 2005-08-01 Celebrex Gaining Bextra's Prescriptions 2005-05-20 Pfizer Trims Projected 2005 Earnings 2005-04-06 Panelists in FDA Drug Vote Tied to Makers 2005-02-25 Vioxx Could Rejoin Painkillers on Market 2005-02-19 Merck Shares Rise on FDA Panel's Decision 2005-02-18 Pfizer: Celebrex Causes No Increased Risk 2005-02-05 Celebrex Prescriptions Sink After Study 2004-12-30 FDA advises more limited use of COX-2 painkillers 2004-12-23 Pfizer shares rise on Celebrex, Aleve trial data 2004-12-21 Poll: Confidence in Drug Safety Remains 2004-12-21 Pfizer Pulling Advertising for Celebrex 2004-12-20 Analysts bet Pfizer's Celebrex won't be withdrawn 2004-12-20 Pfizer Celebrex trial stopped after heart attacks 2004-12-17 US FDA reviewing Celebrex, urges alternatives 2004-12-17 Celebrex Benefits From Vioxx Withdrawal 2004-11-30 FDA Orders Pfizer to Pull 'Wild Thing' Ad 2004-11-15 Pfizer profit rises on blockbuster drugs 2003-01-22 Pfizer to Buy Pharmacia for $60 Billion in Stock 2002-07-15 US drugmakers shine; Schering-Plough misses parade 2001-07-26 Pharmacia profits rise as key drugs surge 2001-07-26 Pharmacia Hits Year Low on Drug Setback 2001-07-21 Merck Cuts Profit Estimates 2001-06-23 Monsanto, Pharmacia & Upjohn Agree To Merge 1999-12-20 Pfizer To Settle Price-Fixing Case for $20M 1999-07-20 Merck's 'Super-Aspirin' Gets FDA Approval 1999-05-21 Most-viewed Pfizer To Settle Price-Fixing Case for $20M 1999-07-20 FDA Approves Celebrex for Spinal Arthritis 2005-08-01 $894 million deal ends pain of Pfizer's lawsuits 2008-10-17 Merck Shares Rise on FDA Panel's Decision 2005-02-18 US drugmakers shine; Schering-Plough misses parade 2001-07-26 Pfizer reaches deal with some Celebrex users: report 2008-05-02 Pfizer's Hank McKinnell replaced as CEO 2006-07-28

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